An ambiguity principle for assigning protein structural domains

An ambiguity principle for assigning protein structural domains

Ambiguity is the quality of being open to several interpretations. For an image, it arises when the contained elements can be delimited in two or more distinct ways, which may cause confusion. We postulate that it also applies to the analysis of protein three-dimensional structure, which consists in dividing the molecule into subunits called domains. Because different definitions of what consti...

Statistical Ambiguity Resolution for Principle-Based Parsing

The goal of syntactic ambiguity resolution is to produce the naturally preferred interpretation of any given input, while limiting computational resources. We present in this paper a statistical pruning device developed for a principle-based parser which attempts to satisfy this goal. We compare the performances of the resulting hybrid parser with an instance of the same parser including a symb...

Discovering Domains Mediating Protein Interactions

Background: Protein-protein interactions do not provide any direct information re‌garding the domains within the proteins that mediate the interactions. The majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. Most of the former studies focus only on interacting do‌main pairs. However they do not consider the in...

Assigning Terms to Domains by Document Classification

In this paper we investigate a number of questions relating to the identification of the domain of a term by domain classification of the document in which the term occurs. We propose and evaluate a straightforward method for domain classification of documents in 24 languages that exploits a multilingual thesaurus and Wikipedia. We investigate and provide quantitative results about the extent t...

Assigning Domains To Speech Recognition Hypotheses